Protein Detail

Protein Information

PDBId & Chain	2X1W : L
Molecule	Vascular endothelial growth factor receptor 2
Residues	196
Sequence
SSE Sequence^*(17)	`EEEEEEEEEEEEEEEEE`

^* Secondary structure Elements (SSE) from N to C terminal of the PDB chain. [SSE: H ("Alpha Helix"); E ("Strands")]

Protein Topology

Topology Information

Protein topology is represented by contact and orientation of secondary structure elements (SSEs). The figure on the left represents the contact map with information on type of orientation two SSEs share (color coded). The matrix can be represented in following string representation.

Contact String
cs [Click here to expand] `Ea.0.Ea.0.Ea.0.Ea.0.0.0.Ea.Ea.Ea.Ea.Ea.Ea-0.0.0.Ea.0.0.Ea.0.0.Ea.0.0.Ep.0.0-0.0.Ep.Ep.0.0.0.0.0.0.0.Ea.Ea.0-0.Ea.Ea.0.0.0.0.0.0.0.0.Ep.0-0.Ep.0.0.0.0.0.0.0.0.0.Ea-0.0.0.0.0.0.0.0.0.Ea.Ep-0.0.0.0.0.0.0.0.0.Ep-Ep.0.0.0.0.0.0.0.0-0.0.0.0.0.0.0.0-0.0.0.0.0.0.0-0.0.0.0.0.0-0.0.0.0.0-0.0.0.0-0.0.0-0.0-0`

Prefence of topology : False

[ Hover over the plot rectangles to know more about SSE-contact ]

Linear Topology Graph : 2X1W_L

Protein Id: 2X1W_L

Figure Detail - Blocks: Helix (rectangles), Strands (triangles); Colormap: Red (N-terminal),--(Green)-- Blue (C-Terminal). Spatial Connectivity by arc Lines [Hover over the image to know the SSE detail]

Topology Graph : 2X1W_L

Protein Id: 2X1W_L

Expand

Figure Detail - Blocks: Helix (circle), Strands (arrow); Colormap: Red (N-terminal), Blue (C-Terminal). Spatial Connectivity by dotted Lines [Hover over the image to know the SSE detail]

Modules in queried Topology

#SSE	SSE string	Contact String	Preferrence	ProteinDB	DomainsDB
3	EEE	Ea.0-0	True	2YFV:C, 2ZJR:U, 3B08:B, 3B08:E, 3B08:H, 3B08:K, 3D2Q:D, 3EGG:D, 3GL6:A, 3HVQ:D, 3KXY:Y, 3MMY:B, 3MMY:D, 3MMY:F, 3MMY:H, 3O7A:A, 3TND:D, 3TND:F, 3ZG9:A, 4EAZ:C, 4EAZ:D, 4LM6:A, 4LM6:C, 4LMS:A, 4LMX:A, 4LMX:C, 4LMX:E, 4LMX:G, 4LMX:I, 4LMX:K, 4MMS:A, 4MMS:C, 4MMS:E, 4Q4W:4, 4QF2:A, 4QF2:B, 4QF2:C, 4QF2:D, 4QF3:A, 4QF3:B, 4WJW:A, 5E4X:A, 5IYZ:E, 5KX5:E, 1D4M:4, 1G3J:B, 1HXS:4, 1J8E:A, 1JY2:O, 1VPZ:A, 1XG0:A, 1XG0:B, 1XU1:R, 2BTI:A,	d1cxxa2, d1k0ra4, d1lv3a_, d1wvka_, d1xg0a_, d1xpaa2, d1xu1r_, d1xu2r_, d2btia_, d2bv3a4, d2glia4, d2gtlm2, d2zjru1, d3ryce_, 1e0aB00, 1g3jD00, 1jy2O00, 1lv3A00, 1wvkA00, 1xg0B00, 2fyuI00, 2gliA04,
3	EEE	0.Ea-0	True	2Y8T:B, 2Y8T:E, 2ZJR:Z, 3H31:A, 3O27:B, 3SF4:D, 3SF4:E, 3SF4:F, 4I6M:D, 4XO1:A, 4YIZ:B, 4YIZ:D, 4YIZ:F, 5DM6:Z, 5ITM:A, 5ITM:B, 5ITM:C, 5ITM:D, 5ITM:E, 5ITM:F, 1AVY:A, 1HLQ:A, 1ICF:I, 1ISU:A, 1PML:A, 2ATC:B, 2DLB:A, 2GGV:A,	d1hlqa_, d1icfi_, d1isua_, d1ppji_, d1rwsa_, d1skza1, d1tdha3, d1yfba1, d2dlba1, d2i9aa2, d2qam01, d2zdra1, d3h31a_, 1avyA00, 1avyB00, 1avyA00, 1avyB00, 1hlqA00, 1icfI00, 1ppjI00, 1rwsA00, 2fd6A02,
3	EEE	0.Ea-Ea	False	3QTE:A, 3QTE:B, 3QTE:C, 5J4S:B, 2J5L:A,	d1bdsa_, d1ut3a_, d2j4wd1, d2nn6i2, 1bdsA00, 1bdsA00,
3	EEE	Ea.0-Ea	False	4C2M:1, 4C2M:L, 4KSN:A, 4SGB:I, 6RXN:A, 2DSX:A, 2RDV:A, 2V3B:B,	d1lkoa2, d1pfva3, d1yuza2, d1zina2, d2cona1, d4sgbi_, 2dsxA00, 4sgbI00,
3	EEE	Ea.Ea-0	True	3FIF:F, 3MLQ:G, 4A94:C, 4EAG:B, 4EAI:B, 4OEL:B, 4PKF:C, 5BWD:C, 5DZD:A, 5K2M:E, 2BZY:A, 2QN5:B, 2V8Q:B,	d1co4a_, d1dl6a_, d1egfa_, d1gl1i_, d1k36a_, d1k81a_, d1ng2a1, d1nvpd2, d1pina1, d1tpga2, d1twfi1, d1twfi2, d2akla2, d2dara2, d2k4xa1, d2v8qb1, 1co4A00, 1dl6A00, 1co4A00, 1dl6A00, 1k36A00, 1nvpD02,
3	EEE	Ea.Ea-Ep	True	2XTT:A, 3CFA:L, 3CFA:M, 3CFA:R, 3CFA:S, 3CFH:L, 3CFH:M, 3CFH:R, 3CFH:S, 3LE4:A, 3MLQ:E, 3MLQ:H, 3TVJ:I, 4F98:A, 4GWT:A, 4N7F:A, 4N7F:B, 4REX:A, 5DZD:B, 5E24:B, 5E24:D, 1NH2:C, 1NVP:C, 2A50:A, 2HIP:A,	d1gl0i_, d1goia1, d1kbea_, d1mkna_, d1nh2c_, d1nh2d2, d1o9aa1, d1rl2a2, d2dk1a1, d2hipa_, d2ho2a1, d2jmfa1, 1kbeA00, 1mknA00, 1nh2C00, 1nvpC00, 1o9aA01,
4	EEEE	Ea.0.Ea-0.0-0	True	3BG4:D, 3UA0:A, 3UCI:A, 4R5R:A, 4R5R:B, 4ZRP:C, 4ZRP:D, 5B4Y:B, 5C13:A, 5C13:G, 5F0E:B, 5F86:B, 5JQP:B, 5KXH:B, 5KY0:B, 5KY4:B, 1J2L:A, 1KIG:L, 1LSL:A, 2QSK:A, 2W2N:E,	d1ataa_, d1b9wa2, d1i07a_, d1j2la_, d1jmab1, d1ppqa_, d1q4ga2, d2i9aa1, d2j01y1, d2qqra2, 1eqgA01, 1fycA00, 1i07A00, 1xkbA01, 2fd6A01,
4	EEEE	0.Ea.0-0.0-0	True	2YNZ:A, 2YNZ:B, 2YNZ:C, 3C9I:A, 3C9I:B, 3C9I:C, 3C9I:D, 3C9I:E, 3C9I:F, 3ZMF:C, 5BU5:A, 5BU5:B, 5BU5:C, 5BU5:D, 5BU5:E, 5BU5:F, 5BU8:A, 5BU8:B,
4	EEEE	Ea.0.Ea-0.Ea-Ep	False	4X0N:B,	d1wfea_, 1wfeA00,
4	EEEE	0.Ea.0-0.Ea-0	False	3EB5:A, 4AUQ:B, 4AUQ:E,
4	EEEE	Ea.0.0-Ea.0-0	False	3U28:B, 2AUS:B,	d3u28b_,
4	EEEE	Ea.Ea.Ea-0.0-0	True	4A94:D, 5JB9:E, 1XDT:R,	d1autl1, d1auua_, d1eaic_, d1g1ta2, d1hx2a_, d1ijqa2, d1m7ja2, d1nzia2, d1szba2, d1tfia_, d1xdtr_, d2bz6l_, d2y5fl_, d3bpse1, 1auuA00, 1auuA00, 1eaiC00, 1hx2A00, 1moxD00, 1nziB02, 1ridA03, 1tfiA00, 1wj2A00, 2bz6L00,
4	EEEE	Ea.Ea.Ea-0.Ep-Ea	True	3TBN:A, 4BV4:L, 4LXR:K, 5AOQ:L, 5AOQ:M,	d1jmab2, 1ccvA00, 1ccvA00,
4	EEEE	Ea.Ea.Ea-Ep.0-Ea	False	4YX7:A, 4YX7:D, 5HCC:D, 5HCD:D,
5	EEEEE	Ea.0.Ea.0-0.0.0-0.0-0	True	3TND:B, 3TND:H, 3ZVK:E, 3ZVK:F, 3ZVK:G, 3ZVK:H, 5K8J:A, 5K8J:D,	d2qqra1,
5	EEEEE	Ea.0.Ea.0-0.0.Ea-0.0-0	False		d1kg1a_,
8	EEEEEEEE	0.Ea.Ea.Ea.Ea.Ea.Ea-Ea.0.0.Ep.0.0-0.0.Ea.Ea.0-0.0.Ep.0-0.0.Ea-Ea.Ep-Ep	False	1T0P:B,

Protein In ProLegoDB with identical/similar Topology

Proteins with Identical Topology

[Same secondary structure composition, contact-pair and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology
2X1W	O	193	Vascular endothelial growth factor receptor 2	View

Protein with similar Topology [same scaffold]

[Same secondary structure composition and contact-pair but of different orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Proteins with topologies of same secondary structure (H/E) component

[Topologies with same secondary structure composition with different contact-pairs and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology
2X1W	N	194	Vascular endothelial growth factor receptor 2	View
2XHA	A	193	Transcription termination/antitermination protein NusG	View
2XHA	B	193	Transcription termination/antitermination protein NusG	View
2ZG1	A	208	Sialic acid-binding Ig-like lectin 5	View
3ATG	A	242	Beta-1,3-glucanase	View
3BWU	C	200	Chaperone protein FimC	View
3DI2	D	196	Interleukin-7 receptor subunit alpha	View
3F7Q	A	214	Integrin beta-4	View
3F7Q	B	214	Integrin beta-4	View
3GNE	A	243	VAL-1	View
3GNE	B	242	VAL-1	View
3H8N	A	195	Killer cell immunoglobulin-like receptor 2DS4	View
3JUU	B	269	Beta-porphyranase B	View
3O12	A	182	Regulation of enolase protein 1	View
3PPE	A	203	Cadherin-5	View
3PQI	A	202	Phi92_gp138	View
3RY4	A	170	Low affinity immunoglobulin gamma Fc region receptor II-a	View
3WYR	A	189	Killer cell immunoglobulin-like receptor 2DL4	View
3ZYR	B	241	Lectin	View
4B0M	M	212	Chaperone protein caf1M	View
4BSJ	A	213	Vascular endothelial growth factor receptor 3	View
4DJM	B	202	Periplasmic chaperone	View
4DJM	G	199	Periplasmic chaperone	View
4DWH	A	197	Chaperone protein FimC	View
4DWH	C	201	Chaperone protein FimC	View
4FXT	A	191	Uncharacterized protein	View
4FXT	B	191	Uncharacterized protein	View
4FXT	C	189	Uncharacterized protein	View
4FXT	D	190	Uncharacterized protein	View
4FXT	E	200	Uncharacterized protein	View
4FXT	F	195	Uncharacterized protein	View
4FXT	G	194	Uncharacterized protein	View
4FXT	H	194	Uncharacterized protein	View
4FXT	I	189	Uncharacterized protein	View
4FXT	J	195	Uncharacterized protein	View
4FXT	K	191	Uncharacterized protein	View
4FXT	L	189	Uncharacterized protein	View
4FXT	M	193	Uncharacterized protein	View
4FXT	N	186	Uncharacterized protein	View
4GBS	A	169	Putative lipoprotein	View
4GBS	B	169	Putative lipoprotein	View
4HBQ	A	206	Mucosal addressin cell adhesion molecule 1	View
4HBQ	B	206	Mucosal addressin cell adhesion molecule 1	View
4JFF	D	197	T-cell receptor alpha chain C region	View
4KKR	A	224	RbmA protein	View
4LD1	A	157	Uncharacterized protein	View
4LL9	A	194	Leukocyte immunoglobulin-like receptor subfamily B member 1	View
4LLA	C	198	Leukocyte immunoglobulin-like receptor subfamily B member 2	View
4NCD	A	211	Gram-negative pili assembly chaperone, N-terminal domain protein	View
4NHU	A	197	T-cell receptor alpha chain C region	View
4NHU	C	199	T-cell receptor alpha chain C region	View
4NN5	B	197	Interleukin-7 receptor subunit alpha	View
4PCH	A	252	VP1	View
4PCH	D	248	VP1	View
4UJ7	A	208	Surface layer protein	View
4WZF	A	240	Possible beta-1,3-glucanase	View
4XW3	A	190	ATP-dependent RNA helicase DDX1	View
4XW3	B	194	ATP-dependent RNA helicase DDX1	View
5DCP	B	158	Filamin-B	View
5DXD	B	233	Putative beta-glucanase	View
5E8D	H	216		View
5EYY	A	239	Mannose/glucose-specific lectin	View
5IHB	B	214	Myeloid cell surface antigen CD33	View
5IHB	D	209	Myeloid cell surface antigen CD33	View
5TU8	B	139	Accumulation associated protein	View
5TU9	B	137	Accumulation associated protein	View
5X4S	A	269	Spike glycoprotein	View
1BM3	H	216	Ig gamma-1 chain C region secreted form	View
1F2Q	A	167	High affinity immunoglobulin epsilon receptor subunit alpha	View
1FNL	A	173	Low affinity immunoglobulin gamma Fc region receptor III-B	View
1L4I	A	189	Chaperone protein FocC	View
1T61	A	223	Collagen alpha-1(IV) chain	View
1T61	C	222	Collagen alpha-2(IV) chain	View
1UKG	A	240	Lectin	View
1VCA	A	199	Vascular cell adhesion protein 1	View
1YNL	H	215	Igh protein	View
2A38	A	194	Titin	View
2D3V	A	177	Leukocyte immunoglobulin-like receptor subfamily A member 5	View
2GW5	A	184	Leukocyte immunoglobulin-like receptor subfamily B member 2	View
2H32	H	211		View
2HYK	A	237	Beta-1,3-glucanase	View
2J43	A	216	Pullulanase	View
2J44	A	217	Putative alkaline amylopullulanase	View
2J8H	A	195	Titin	View
2WJR	A	204	Probable N-acetylneuraminic acid outer membrane channel protein NanC	View
2WV3	A	188	Neuroplastin	View
4MS8	C	196		View

Topology view of query protein [ProLego results]

2X1W : L

Topology Information