Protein Detail

Protein Information

PDBId & Chain	2X18 : H
Molecule	RAC-gamma serine/threonine-protein kinase
Residues	116
Sequence
SSE Sequence^*(8)	`EEEEEEEH`

^* Secondary structure Elements (SSE) from N to C terminal of the PDB chain. [SSE: H ("Alpha Helix"); E ("Strands")]

Protein Topology

Topology Information

Protein topology is represented by contact and orientation of secondary structure elements (SSEs). The figure on the left represents the contact map with information on type of orientation two SSEs share (color coded). The matrix can be represented in following string representation.

Contact String
cs [Click here to expand] `Ea.Ea.Ea.0.Ea.Ea.0-0.Ep.0.0.0.Cp-Ea.0.0.Ea.Ca-0.0.0.0-0.Ea.Ca-Ea.Cp-Ca`

Prefence of topology : False

[ Hover over the plot rectangles to know more about SSE-contact ]

Linear Topology Graph : 2X18_H

Protein Id: 2X18_H

Figure Detail - Blocks: Helix (rectangles), Strands (triangles); Colormap: Red (N-terminal),--(Green)-- Blue (C-Terminal). Spatial Connectivity by arc Lines [Hover over the image to know the SSE detail]

Topology Graph : 2X18_H

Protein Id: 2X18_H

Expand

Figure Detail - Blocks: Helix (circle), Strands (arrow); Colormap: Red (N-terminal), Blue (C-Terminal). Spatial Connectivity by dotted Lines [Hover over the image to know the SSE detail]

Modules in queried Topology

#SSE	SSE string	Contact String	Preferrence	ProteinDB	DomainsDB
3	EEE	Ea.Ea-0	True	3FIF:F, 3MLQ:G, 4A94:C, 4EAG:B, 4EAI:B, 4OEL:B, 4PKF:C, 5BWD:C, 5DZD:A, 5K2M:E, 2BZY:A, 2QN5:B, 2V8Q:B,	d1co4a_, d1dl6a_, d1egfa_, d1gl1i_, d1k36a_, d1k81a_, d1ng2a1, d1nvpd2, d1pina1, d1tpga2, d1twfi1, d1twfi2, d2akla2, d2dara2, d2k4xa1, d2v8qb1, 1co4A00, 1dl6A00, 1co4A00, 1dl6A00, 1k36A00, 1nvpD02,
3	EEE	Ea.Ea-Ep	True	2XTT:A, 3CFA:L, 3CFA:M, 3CFA:R, 3CFA:S, 3CFH:L, 3CFH:M, 3CFH:R, 3CFH:S, 3LE4:A, 3MLQ:E, 3MLQ:H, 3TVJ:I, 4F98:A, 4GWT:A, 4N7F:A, 4N7F:B, 4REX:A, 5DZD:B, 5E24:B, 5E24:D, 1NH2:C, 1NVP:C, 2A50:A, 2HIP:A,	d1gl0i_, d1goia1, d1kbea_, d1mkna_, d1nh2c_, d1nh2d2, d1o9aa1, d1rl2a2, d2dk1a1, d2hipa_, d2ho2a1, d2jmfa1, 1kbeA00, 1mknA00, 1nh2C00, 1nvpC00, 1o9aA01,
3	EEE	Ea.0-0	True	2YFV:C, 2ZJR:U, 3B08:B, 3B08:E, 3B08:H, 3B08:K, 3D2Q:D, 3EGG:D, 3GL6:A, 3HVQ:D, 3KXY:Y, 3MMY:B, 3MMY:D, 3MMY:F, 3MMY:H, 3O7A:A, 3TND:D, 3TND:F, 3ZG9:A, 4EAZ:C, 4EAZ:D, 4LM6:A, 4LM6:C, 4LMS:A, 4LMX:A, 4LMX:C, 4LMX:E, 4LMX:G, 4LMX:I, 4LMX:K, 4MMS:A, 4MMS:C, 4MMS:E, 4Q4W:4, 4QF2:A, 4QF2:B, 4QF2:C, 4QF2:D, 4QF3:A, 4QF3:B, 4WJW:A, 5E4X:A, 5IYZ:E, 5KX5:E, 1D4M:4, 1G3J:B, 1HXS:4, 1J8E:A, 1JY2:O, 1VPZ:A, 1XG0:A, 1XG0:B, 1XU1:R, 2BTI:A,	d1cxxa2, d1k0ra4, d1lv3a_, d1wvka_, d1xg0a_, d1xpaa2, d1xu1r_, d1xu2r_, d2btia_, d2bv3a4, d2glia4, d2gtlm2, d2zjru1, d3ryce_, 1e0aB00, 1g3jD00, 1jy2O00, 1lv3A00, 1wvkA00, 1xg0B00, 2fyuI00, 2gliA04,
3	EEE	0.Ea-0	True	2Y8T:B, 2Y8T:E, 2ZJR:Z, 3H31:A, 3O27:B, 3SF4:D, 3SF4:E, 3SF4:F, 4I6M:D, 4XO1:A, 4YIZ:B, 4YIZ:D, 4YIZ:F, 5DM6:Z, 5ITM:A, 5ITM:B, 5ITM:C, 5ITM:D, 5ITM:E, 5ITM:F, 1AVY:A, 1HLQ:A, 1ICF:I, 1ISU:A, 1PML:A, 2ATC:B, 2DLB:A, 2GGV:A,	d1hlqa_, d1icfi_, d1isua_, d1ppji_, d1rwsa_, d1skza1, d1tdha3, d1yfba1, d2dlba1, d2i9aa2, d2qam01, d2zdra1, d3h31a_, 1avyA00, 1avyB00, 1avyA00, 1avyB00, 1hlqA00, 1icfI00, 1ppjI00, 1rwsA00, 2fd6A02,
3	EEH	Ea.0-Cp	True	2V89:A,	d1hnra_, d1vyxa_, d2j9ub1, d2v89a_, 1hnrA00, 1vyxA00,
4	EEEE	Ea.Ea.Ea-0.Ep-Ea	True	3TBN:A, 4BV4:L, 4LXR:K, 5AOQ:L, 5AOQ:M,	d1jmab2, 1ccvA00, 1ccvA00,
4	EEEE	Ea.0.Ea-0.0-0	True	3BG4:D, 3UA0:A, 3UCI:A, 4R5R:A, 4R5R:B, 4ZRP:C, 4ZRP:D, 5B4Y:B, 5C13:A, 5C13:G, 5F0E:B, 5F86:B, 5JQP:B, 5KXH:B, 5KY0:B, 5KY4:B, 1J2L:A, 1KIG:L, 1LSL:A, 2QSK:A, 2W2N:E,	d1ataa_, d1b9wa2, d1i07a_, d1j2la_, d1jmab1, d1ppqa_, d1q4ga2, d2i9aa1, d2j01y1, d2qqra2, 1eqgA01, 1fycA00, 1i07A00, 1xkbA01, 2fd6A01,
4	EEEE	0.Ea.Ea-0.0-Ea	False	4LE9:A,	d1xi7a_,
4	EEEH	Ea.Ea.0-0.Cp-Ca	True	3BID:A, 3BID:B, 3BID:C, 3BID:E, 3BID:F, 3BID:G, 3N52:D, 4HCS:A, 1M8A:A, 1NR4:A,	d1m8aa_, d1nr4a_, d2k49a2, d2nn6f2, d3bida1, 1nr4C00,
5	EEEEE	Ea.Ea.0.Ea-Ep.0.0-0.0-0	False	3CAM:A, 3CAM:B,	d1o12a1, 1o12A01,

Protein In ProLegoDB with identical/similar Topology

Proteins with Identical Topology

[Same secondary structure composition, contact-pair and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Protein with similar Topology [same scaffold]

[Same secondary structure composition and contact-pair but of different orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Proteins with topologies of same secondary structure (H/E) component

[Topologies with same secondary structure composition with different contact-pairs and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology
2X18	A	111	RAC-gamma serine/threonine-protein kinase	View
2X18	B	114	RAC-gamma serine/threonine-protein kinase	View
2X18	C	115	RAC-gamma serine/threonine-protein kinase	View
2X18	D	115	RAC-gamma serine/threonine-protein kinase	View
2X18	E	116	RAC-gamma serine/threonine-protein kinase	View
2X18	F	111	RAC-gamma serine/threonine-protein kinase	View
2X18	G	115	RAC-gamma serine/threonine-protein kinase	View
2Y8G	A	123	Ran-binding protein 3	View
2Y8G	B	119	Ran-binding protein 3	View
2Z3Q	B	81	Interleukin-15 receptor subunit alpha	View
3AWU	B	78	MelC	View
3CXB	B	103	Pleckstrin homology domain-containing family M member 2	View
3ECG	A	99	Gag-Pol polyprotein	View
3ECG	B	99	Gag-Pol polyprotein	View
3EE7	A	106	Replicase polyprotein 1a	View
3EE7	B	115	Replicase polyprotein 1a	View
3EE7	C	110	Replicase polyprotein 1a	View
3EE7	D	112	Replicase polyprotein 1a	View
3GGU	A	99	Gag-Pol polyprotein	View
3GGU	B	99	Gag-Pol polyprotein	View
3ID9	A	120	MutT/NUDIX	View
3IXO	A	99	Gag-Pol polyprotein	View
3IXO	B	99	Gag-Pol polyprotein	View
3MWS	A	99	Pol protein	View
3MWS	B	99	Pol protein	View
3N7C	A	107	ABR034Wp	View
3N7C	B	101	ABR034Wp	View
3OGP	A	112	Pol polyprotein	View
3OGP	B	112	Pol polyprotein	View
3QWM	A	127	IQ motif and SEC7 domain-containing protein 1	View
3RCP	A	96	Pleckstrin homology domain-containing family A member 3	View
3SPK	A	99	Pol protein	View
3SPK	B	99	Pol protein	View
3T3C	A	99	Gag-Pol polyprotein	View
3T3C	B	99	Gag-Pol polyprotein	View
3TJQ	A	106	Serine protease HTRA1	View
3TRE	A	124	Elongation factor P	View
3TTP	A	99	Gag-Pol polyprotein	View
3TTP	B	99	Gag-Pol polyprotein	View
3U7S	A	99	Gag-Pol polyprotein	View
3U7S	B	99	Gag-Pol polyprotein	View
3VUB	A	101	Toxin CcdB	View
3WYF	B	144	Ran-specific GTPase-activating protein 2	View
3WYF	E	142	Ran-specific GTPase-activating protein 2	View
3ZH5	A	132	PROTEIN E	View
3ZH5	B	132	PROTEIN E	View
3ZPN	B	107	Photosystem II reaction center Psb28 protein	View
4A6H	A	108	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1	View
4A6H	B	108	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1	View
4A6H	C	107	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1	View
4A6H	D	106	Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1	View
4B6H	B	101	mRNA-decapping enzyme 1A	View
4ELY	D	98	CcdB	View
4ELZ	C	104	CcdB	View
4ELZ	D	102	CcdB	View
4HHV	A	103	Collagen type IV alpha-3-binding protein	View
4HHV	B	101	Collagen type IV alpha-3-binding protein	View
4I86	A	102	Cellulose synthase 1	View
4L6E	A	120	E3 SUMO-protein ligase RanBP2	View
4NPU	A	99	Protease	View
4NPU	B	99	Protease	View
4QJ6	A	99	Gag-Pol polyprotein	View
4QJ6	B	99	Gag-Pol polyprotein	View
4QJ6	C	99	Gag-Pol polyprotein	View
4QJ6	D	99	Gag-Pol polyprotein	View
4RVJ	A	99	Protease	View
4RVJ	B	99	Protease	View
4RVJ	C	99	Protease	View
4RVJ	D	99	Protease	View
4WSF	A	111	Serine/threonine-protein phosphatase 4 regulatory subunit 3	View
5B18	A	99	Pol protein	View
5B18	B	99	Pol protein	View
5B18	C	99	Pol protein	View
5B18	D	99	Pol protein	View
5C79	A	104	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1	View
5C79	B	103	Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1	View
5CLL	B	139	E3 SUMO-protein ligase RanBP2	View
5CLL	D	139	E3 SUMO-protein ligase RanBP2	View
5HIZ	A	96	Replicase polyprotein 1ab	View
5HIZ	B	96	Replicase polyprotein 1ab	View
5MR1	A	101	Interactor protein for cytohesin exchange factors 1	View
5T2E	A	99	Protease	View
5UCT	A	99	Endoribonuclease MazF3	View
5UCT	B	100	Endoribonuclease MazF3	View
5WYG	A	105	Probable endoribonuclease MazF7	View
5WYG	C	106	Probable endoribonuclease MazF7	View
1AZ5	A	95	Gag-Pol polyprotein	View
1BDQ	A	99	Gag-Pol polyprotein	View
1FAO	A	100	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide	View
1J0W	A	97	Docking protein 5	View
1SGU	A	99	Gag-Pol polyprotein	View
1U5D	A	108	Src kinase-associated phosphoprotein 1	View
1U5F	A	111	Src kinase-associated phosphoprotein 2	View
1UPQ	A	107	Pleckstrin homology domain-containing family A member 4	View
1ZC3	B	109	Exocyst complex component 8	View
2FDD	A	99	Pol protein	View
2GMQ	A	96	EF0006	View
2HAH	A	112	POL protein	View
2HC0	A	99	Protease	View
2HS1	A	99	Protease	View
2I5F	A	99	Pleckstrin	View
2J97	A	98	Replicase polyprotein 1ab	View
2P3C	A	98	Protease	View
2P3D	A	99	Protease	View
2R8N	A	99	Gag-Pol polyprotein	View
2RKF	A	99	Pol protein	View
2W2X	C	109	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2	View

Topology view of query protein [ProLego results]

2X18 : H

Topology Information