ProLego Protein as lego blocks ...
 

Topology Browser  [Search with followings]

Structure class: [A: Alpha (all helix); B: Beta (all strands); AB: alpha-beta (mixed)]

SS composition: [SSE: Secondary structue from N to C terminal of protein chain]

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# Helix: [Number con alpha helix in protein chain]

# Strands: [Number of beta strands in protein chain]

Minimum number of SSE contact pair: [Least number of Secondary structure pairwise contacts]

Topology preferance status: [True/False Preferred topologies are most frequently occurred scaffolds in a SSE composition]

(search in combination or with any one input)

 
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Topology List   [Click on a Topology String to explore]

Str Class Sse String H E Topology String Paired Contacts Is Preferred topoGrp statSig
AB EHEEHEEEHEEEEEHEEEEEHEEEEEHHHHEEHEHEEEEH 12 28 Topology 83 ✘ False
AB HEEEEHHHHEHHEEHEHHEEEHHEEEEEH 13 16 Topology 59 ✘ False
AB HEEEEHHHHEHHEEHEHHEEEHHEEEEEH 13 16 Topology 48 ✘ False
AB EHEEEHEHHHEEHEHHHHEEHEE 11 12 Topology 55 ✘ False
AB EHEEEHEHHHEEHEHHHHEEHEE 11 12 Topology 57 ✘ False
AB EEEHEEE 1 6 Topology 7 ✘ False
AB EEEHEEE 1 6 Topology 8 ✘ False
AB EEEHEEE 1 6 Topology 6 ✔ False
AB EEEHEEE 1 6 Topology 11 ✘ False
AB EEEHEEE 1 6 Topology 9 ✘ False
AB EEEHEEE 1 6 Topology 9 ✘ False
AB EEEHEEE 1 6 Topology 8 ✘ False
AB EEEHEEE 1 6 Topology 6 ✘ False
AB EEEHEEE 1 6 Topology 4 ✘ False
AB EEEHEEE 1 6 Topology 7 ✘ False
AB EEEHEEE 1 6 Topology 12 ✘ False
AB EEEHEEE 1 6 Topology 4 ✘ False
AB EEEHEEE 1 6 Topology 12 ✔ False
AB EEEHEEE 1 6 Topology 14 ✘ False
AB EEEHEEE 1 6 Topology 10 ✘ False
Table Description [Click here to expand]

Above table lists all the available topologies in the ProLego database. Each topology (row in the table), refers to a possible contact combination of secondary structure elements (SSEs). The table column headers can be read as following,

  • topClass:  Structure Class [A: All alpha; B: all Beta, AB: alpha beta Mix]
  • Helix (H):  Number of helices in structure.
  • Strands (E):  Number of beta-strands in structure.
  • SSE string:  SSE string represents the occurences of Heleix(H) and Beta-Strands(E) in sequce from N to C terminal.
  • Paired Contact:  Number of pair-wise contact in a topology [varies from 1 to n*(n-1)/2 ; where n is number of secondary structures (H and E)]
  • Topology String:  The link for vizualising and detail information on a particular topology
  • Is Preferred:  Prefernce of a Topology in the group of SSE
  • topoGrp statSig:  Statistical significance of a topology class