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Topology Browser  [Search with followings]

Structure class: [A: Alpha (all helix); B: Beta (all strands); AB: alpha-beta (mixed)]

SS composition: [SSE: Secondary structue from N to C terminal of protein chain]

# Helix: [Number con alpha helix in protein chain]

# Strands: [Number of beta strands in protein chain]

Minimum number of SSE contact pair: [Least number of Secondary structure pairwise contacts]

Topology preferance status: [True/False Preferred topologies are most frequently occurred scaffolds in a SSE composition]

(search in combination or with any one input)

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Topology List   [Click on a Topology String to explore]

Str Class Sse String H E Topology String Paired Contacts Is Preferred topoGrp statSig
AB EEEEHHEEEHHHHEHEHEEHEEHEEHEEEEHHEEHEHEHHEH 18 24 Topology 86 False
AB EEEHEEH 2 5 Topology 8 False
AB EEEHEEH 2 5 Topology 16 False
AB EEEHEEH 2 5 Topology 8 False
AB EEEHEEH 2 5 Topology 10 False
AB EEEHEEH 2 5 Topology 11 False
AB EEEHEEH 2 5 Topology 10 False
AB EEEHEEH 2 5 Topology 7 False
AB EEEHEEH 2 5 Topology 10 False
AB EEEHEEH 2 5 Topology 8 False
AB EEEHEEH 2 5 Topology 10 False
AB HEHEEHEHEHEHHHEEEEEEHHEEEEEEE 10 19 Topology 57 False
AB HEHEEHEHEHEHHHEEEEEEHHEEEEEEE 10 19 Topology 58 False
AB HEHEEHEHEHEHHHEEEEEEHHEEEEEEE 10 19 Topology 59 False
AB HEHEEHEHEHEHHHEEEEEEHHEEEEEEE 10 19 Topology 52 False
AB HEHEEHEHEHEHHHEEEEEEHHEEEEEEE 10 19 Topology 56 False
AB EEEHEHHHEEHEEHEEEEEEEHEEEEEEH 8 21 Topology 48 False
AB EEEHEHHHEEHEEHEEEEEEEHEEEEEEH 8 21 Topology 45 False
AB EEEHEHHHEEHEEHEEEEEEEHEEEEEEH 8 21 Topology 48 False
AB HHHEEEEEEEEEEEEEEEEEE 3 18 Topology 23 False

Above table lists all the available topologies in the ProLego database. Each topology (row in the table), refers to a possible contact combination of secondary structure elements (SSEs). The table column headers can be read as following,

  • topClass:  Structure Class [A: All alpha; B: all Beta, AB: alpha beta Mix]
  • Helix (H):  Number of helices in structure.
  • Strands (E):  Number of beta-strands in structure.
  • SSE string:  SSE string represents the occurences of Heleix(H) and Beta-Strands(E) in sequce from N to C terminal.
  • Paired Contact:  Number of pair-wise contact in a topology [varies from 1 to n*(n-1)/2 ; where n is number of secondary structures (H and E)]
  • Topology String:  The link for vizualising and detail information on a particular topology
  • Is Preferred:  Prefernce of a Topology in the group of SSE
  • topoGrp statSig:  Statistical significance of a topology class