Protein Detail

Protein Information

PDBId & Chain	2PKA : A
Molecule	Glandular kallikrein
Residues	78
Sequence
SSE Sequence^*(5)	`EEEEE`

^* Secondary structure Elements (SSE) from N to C terminal of the PDB chain. [SSE: H ("Alpha Helix"); E ("Strands")]

Protein Topology

Topology Information

Protein topology is represented by contact and orientation of secondary structure elements (SSEs). The figure on the left represents the contact map with information on type of orientation two SSEs share (color coded). The matrix can be represented in following string representation.

Contact String
cs [Click here to expand] `Ea.Ea.0.Ea-Ep.0.0-Ea.0-0`

Prefence of topology : False

[ Hover over the plot rectangles to know more about SSE-contact ]

Linear Topology Graph : 2PKA_A

Protein Id: 2PKA_A

Figure Detail - Blocks: Helix (rectangles), Strands (triangles); Colormap: Red (N-terminal),--(Green)-- Blue (C-Terminal). Spatial Connectivity by arc Lines [Hover over the image to know the SSE detail]

Topology Graph : 2PKA_A

Protein Id: 2PKA_A

Expand

Figure Detail - Blocks: Helix (circle), Strands (arrow); Colormap: Red (N-terminal), Blue (C-Terminal). Spatial Connectivity by dotted Lines [Hover over the image to know the SSE detail]

Modules in queried Topology

#SSE	SSE string	Contact String	Preferrence	ProteinDB	DomainsDB
3	EEE	Ea.Ea-Ep	True	2XTT:A, 3CFA:L, 3CFA:M, 3CFA:R, 3CFA:S, 3CFH:L, 3CFH:M, 3CFH:R, 3CFH:S, 3LE4:A, 3MLQ:E, 3MLQ:H, 3TVJ:I, 4F98:A, 4GWT:A, 4N7F:A, 4N7F:B, 4REX:A, 5DZD:B, 5E24:B, 5E24:D, 1NH2:C, 1NVP:C, 2A50:A, 2HIP:A,	d1gl0i_, d1goia1, d1kbea_, d1mkna_, d1nh2c_, d1nh2d2, d1o9aa1, d1rl2a2, d2dk1a1, d2hipa_, d2ho2a1, d2jmfa1, 1kbeA00, 1mknA00, 1nh2C00, 1nvpC00, 1o9aA01,
3	EEE	Ea.0-0	True	2YFV:C, 2ZJR:U, 3B08:B, 3B08:E, 3B08:H, 3B08:K, 3D2Q:D, 3EGG:D, 3GL6:A, 3HVQ:D, 3KXY:Y, 3MMY:B, 3MMY:D, 3MMY:F, 3MMY:H, 3O7A:A, 3TND:D, 3TND:F, 3ZG9:A, 4EAZ:C, 4EAZ:D, 4LM6:A, 4LM6:C, 4LMS:A, 4LMX:A, 4LMX:C, 4LMX:E, 4LMX:G, 4LMX:I, 4LMX:K, 4MMS:A, 4MMS:C, 4MMS:E, 4Q4W:4, 4QF2:A, 4QF2:B, 4QF2:C, 4QF2:D, 4QF3:A, 4QF3:B, 4WJW:A, 5E4X:A, 5IYZ:E, 5KX5:E, 1D4M:4, 1G3J:B, 1HXS:4, 1J8E:A, 1JY2:O, 1VPZ:A, 1XG0:A, 1XG0:B, 1XU1:R, 2BTI:A,	d1cxxa2, d1k0ra4, d1lv3a_, d1wvka_, d1xg0a_, d1xpaa2, d1xu1r_, d1xu2r_, d2btia_, d2bv3a4, d2glia4, d2gtlm2, d2zjru1, d3ryce_, 1e0aB00, 1g3jD00, 1jy2O00, 1lv3A00, 1wvkA00, 1xg0B00, 2fyuI00, 2gliA04,
3	EEE	0.Ea-0	True	2Y8T:B, 2Y8T:E, 2ZJR:Z, 3H31:A, 3O27:B, 3SF4:D, 3SF4:E, 3SF4:F, 4I6M:D, 4XO1:A, 4YIZ:B, 4YIZ:D, 4YIZ:F, 5DM6:Z, 5ITM:A, 5ITM:B, 5ITM:C, 5ITM:D, 5ITM:E, 5ITM:F, 1AVY:A, 1HLQ:A, 1ICF:I, 1ISU:A, 1PML:A, 2ATC:B, 2DLB:A, 2GGV:A,	d1hlqa_, d1icfi_, d1isua_, d1ppji_, d1rwsa_, d1skza1, d1tdha3, d1yfba1, d2dlba1, d2i9aa2, d2qam01, d2zdra1, d3h31a_, 1avyA00, 1avyB00, 1avyA00, 1avyB00, 1hlqA00, 1icfI00, 1ppjI00, 1rwsA00, 2fd6A02,
4	EEEE	Ea.0.Ea-0.0-0	True	3BG4:D, 3UA0:A, 3UCI:A, 4R5R:A, 4R5R:B, 4ZRP:C, 4ZRP:D, 5B4Y:B, 5C13:A, 5C13:G, 5F0E:B, 5F86:B, 5JQP:B, 5KXH:B, 5KY0:B, 5KY4:B, 1J2L:A, 1KIG:L, 1LSL:A, 2QSK:A, 2W2N:E,	d1ataa_, d1b9wa2, d1i07a_, d1j2la_, d1jmab1, d1ppqa_, d1q4ga2, d2i9aa1, d2j01y1, d2qqra2, 1eqgA01, 1fycA00, 1i07A00, 1xkbA01, 2fd6A01,

Protein In ProLegoDB with identical/similar Topology

Proteins with Identical Topology

[Same secondary structure composition, contact-pair and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Protein with similar Topology [same scaffold]

[Same secondary structure composition and contact-pair but of different orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Proteins with topologies of same secondary structure (H/E) component

[Topologies with same secondary structure composition with different contact-pairs and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology
2X3W	D	56	Protein kinase C and casein kinase substrate in neurons protein 1	View
2XMF	A	60	Unconventional myosin-Ie	View
2Y5P	D	72	Internalin B	View
2YDL	A	67	SH3 domain-containing kinase-binding protein 1	View
2Z0W	A	72	CAP-Gly domain-containing linker protein 4	View
3A0J	A	73	Cold shock protein	View
3A0J	B	73	Cold shock protein	View
3BK3	C	67	Crossveinless 2	View
3BK3	D	67	Crossveinless 2	View
3C4S	A	57	Ssl0352 protein	View
3C4S	B	55	Ssl0352 protein	View
3CAM	A	65	Cold-shock domain family protein	View
3CAM	B	65	Cold-shock domain family protein	View
3CP0	A	62	Membrane protein implicated in regulation of membrane protease activity	View
3CQT	A	58	Tyrosine-protein kinase Fyn	View
3FEV	A	65	Three-finger muscarinic toxin 7	View
3FEV	B	65	Three-finger muscarinic toxin 7	View
3FEV	C	65	Three-finger muscarinic toxin 7	View
3FIF	A	52	Uncharacterized lipoprotein YgdR	View
3FIF	B	53	Uncharacterized lipoprotein YgdR	View
3FIF	C	54	Uncharacterized lipoprotein YgdR	View
3FIF	D	54	Uncharacterized lipoprotein YgdR	View
3FIF	E	49	Uncharacterized lipoprotein YgdR	View
3FIF	G	54	Uncharacterized lipoprotein YgdR	View
3FIF	H	52	Uncharacterized lipoprotein YgdR	View
3HH7	A	65	Haditoxin	View
3HH7	B	65	Haditoxin	View
3I2Z	A	71	RNA chaperone, negative regulator of cspA transcription	View
3I2Z	B	67	RNA chaperone, negative regulator of cspA transcription	View
3I35	A	57	LIM and SH3 domain protein 1	View
3IPF	A	69	Putative uncharacterized protein	View
3IPF	B	65	Putative uncharacterized protein	View
3IQL	A	66	Endophilin-A1	View
3IQL	B	67	Endophilin-A1	View
3KFD	I	66	TGF-beta receptor type-1	View
3KFD	J	70	TGF-beta receptor type-1	View
3KFD	K	66	TGF-beta receptor type-1	View
3KFD	L	70	TGF-beta receptor type-1	View
3KXT	A	56	Chromatin protein Cren7	View
3LAZ	A	94	Galactarate dehydratase (L-threo-forming)	View
3LAZ	B	94	Galactarate dehydratase (L-threo-forming)	View
3M0U	A	58	Spectrin alpha chain, non-erythrocytic 1	View
3MJG	A	97	Platelet-derived growth factor subunit B	View
3NDS	A	62	Short neurotoxin 1	View
3NEQ	A	66	Three-finger muscarinic toxin 7	View
3NEQ	B	66	Three-finger muscarinic toxin 7	View
3NFG	B	119	Uncharacterized protein	View
3NFG	D	119	Uncharacterized protein	View
3NFG	F	119	Uncharacterized protein	View
3NFG	J	119	Uncharacterized protein	View
3NFG	L	119	Uncharacterized protein	View
3NFG	N	119	Uncharacterized protein	View
3NFG	P	118	Uncharacterized protein	View
3NGP	A	57	Spectrin alpha chain, non-erythrocytic 1	View
3OW2	P	95	50S ribosomal protein L21e	View
3P8D	A	53	PHD finger protein 20	View
3P8D	B	53	PHD finger protein 20	View
3PF4	A	66	Cold shock protein CspB	View
3PF4	B	66	Cold shock protein CspB	View
3PLC	A	54	Beta-cardiotoxin CTX27	View
3PLC	B	59	Beta-cardiotoxin CTX27	View
3PLC	C	59	Beta-cardiotoxin CTX27	View
3PZ8	H	81	Segment polarity protein dishevelled homolog DVL-1	View
3QR7	A	115	Spike protein	View
3QR7	B	115	Spike protein	View
3REA	B	60	Tyrosine-protein kinase HCK	View
3REA	D	60	Tyrosine-protein kinase HCK	View
3RNJ	A	67	Brain-specific angiogenesis inhibitor 1-associated protein 2	View
3S6N	G	55	Small nuclear ribonucleoprotein G	View
3S6W	A	52	Tudor domain-containing protein 3	View
3SD4	A	69	PHD finger protein 20	View
3SD4	B	69	PHD finger protein 20	View
3TDQ	A	83	Uncharacterized protein	View
3U23	A	56	CD2-associated protein	View
3UA7	A	63	Tyrosine-protein kinase Fyn	View
3UA7	B	63	Tyrosine-protein kinase Fyn	View
3UA7	C	59	Tyrosine-protein kinase Fyn	View
3UA7	D	61	Tyrosine-protein kinase Fyn	View
3UFF	B	65	Protein kinase C delta type	View
3ULJ	A	87	Uncharacterized protein	View
3ULJ	B	90	Uncharacterized protein	View
3ULR	B	64	Src substrate cortactin	View
3VPB	E	56	Alpha-aminoadipate/glutamate carrier protein LysW	View
3VPB	F	56	Alpha-aminoadipate/glutamate carrier protein LysW	View
3VTO	A	99	Baseplate puncturing device gp45	View
3VTO	B	110	Baseplate puncturing device gp45	View
3VTO	C	109	Baseplate puncturing device gp45	View
3VTO	P	103	Baseplate puncturing device gp45	View
3VTO	Q	108	Baseplate puncturing device gp45	View
3VTO	R	103	Baseplate puncturing device gp45	View
3VTS	A	61	Three-finger hemachatoxin	View
3VTS	B	61	Three-finger hemachatoxin	View
3WWL	A	54	Alpha-aminoadipate carrier protein LysW	View
3WWN	B	54	OrfF	View
3ZXC	A	71	Single insulin-like growth factor-binding domain protein-1	View
3ZXC	B	74	Single insulin-like growth factor-binding domain protein-1	View
4A4I	A	84	Protein lin-28 homolog B	View
4A4I	B	85	Protein lin-28 homolog B	View
4AG1	C	63		View
4B6D	A	60	Rac GTPase-activating protein 1	View
4B6D	B	57	Rac GTPase-activating protein 1	View
4B6D	C	60	Rac GTPase-activating protein 1	View
4B6D	D	60	Rac GTPase-activating protein 1	View
4B6D	E	57	Rac GTPase-activating protein 1	View
4B6D	F	60	Rac GTPase-activating protein 1	View
4C92	G	75	U6 snRNA-associated Sm-like protein LSm7	View
4CAH	B	109	Dysferlin	View
4CC2	A	64	Dynamin-binding protein	View
4CC2	C	62	Dynamin-binding protein	View
4DO8	A	66	Three-finger muscarinic toxin 1	View
4DO8	B	66	Three-finger muscarinic toxin 1	View
4E6R	A	53	Cytoplasmic protein NCK2	View
4E6R	B	53	Cytoplasmic protein NCK2	View
4EMH	A	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	B	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	C	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	D	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	E	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	F	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	G	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	H	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	I	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	J	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	K	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	L	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	M	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	N	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	O	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	P	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	Q	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	R	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	T	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	U	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	V	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	W	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	X	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMH	Y	58	Probable U6 snRNA-associated Sm-like protein LSm4	View
4EMK	C	58	U6 snRNA-associated Sm-like protein LSm7	View
4F14	A	56	Nebulette	View
4F7U	G	68	Small nuclear ribonucleoprotein G	View
4F7U	J	67	Small nuclear ribonucleoprotein G	View
4FDB	A	92	Primosomal replication protein n	View
4FKD	A	65	Protein kinase C theta type	View
4GLM	A	58	Dynamin-binding protein	View
4GLM	B	57	Dynamin-binding protein	View
4GLM	C	56	Dynamin-binding protein	View
4GLM	D	57	Dynamin-binding protein	View
4H4N	A	62	Uncharacterized protein	View
4HAE	A	66	Chromodomain Y-like protein 2	View
4HCZ	A	58	PHD finger protein 1	View
4HCZ	B	57	PHD finger protein 1	View
4IYE	A	66	Toxin AdTx1	View
4J9F	A	62	Tyrosine-protein kinase ABL1	View
4J9F	C	57	Tyrosine-protein kinase ABL1	View
4J9F	E	60	Tyrosine-protein kinase ABL1	View
4KT0	E	68	Photosystem I reaction center subunit IV	View
4LM9	A	132	Nucleoprotein	View
4LNP	A	61	Sorbin and SH3 domain-containing protein 1	View
4M7D	A	65	U6 snRNA-associated Sm-like protein LSm8	View
4M7D	C	77	U6 snRNA-associated Sm-like protein LSm3	View
4MN5	A	98	Sensor protein kinase WalK	View
4MN5	B	96	Sensor protein kinase WalK	View
4N8X	3	99	Carbon dioxide concentrating mechanism protein	View
4N8X	C	98	Carbon dioxide concentrating mechanism protein	View
4N8X	K	98	Carbon dioxide concentrating mechanism protein	View
4OM5	A	60	Cytotoxin 4	View
4OM5	B	60	Cytotoxin 4	View
4OM5	C	60	Cytotoxin 4	View
4OM5	D	60	Cytotoxin 4	View
4OMO	A	61	Proto-oncogene tyrosine-protein kinase Src	View
4OMO	B	59	Proto-oncogene tyrosine-protein kinase Src	View
4ORZ	A	56	Tyrosine-protein kinase HCK	View
4PKF	B	69	TutG	View
4PLI	A	57	Protein MRG2	View
4PLI	B	57	Protein MRG2	View
4QQB	X	72	Upstream of N-ras, isoform A	View
4QQB	Y	72	Upstream of N-ras, isoform A	View
4RKU	E	63	Putative uncharacterized protein	View
4RUD	A	58	Three-finger toxin 3b	View
4RUD	B	58	Three-finger toxin 3b	View
4UD1	A	133	N protein	View
4UD1	B	133	N protein	View
4UD1	C	133	N protein	View
4UD1	D	112	N protein	View
4WCI	A	59	CD2-associated protein	View
4WCI	C	63	CD2-associated protein	View
4WCI	E	63	CD2-associated protein	View
4X9C	A	57	Uncharacterized protein MJ1435	View
4X9C	B	58	Uncharacterized protein MJ1435	View
4X9C	C	58	Uncharacterized protein MJ1435	View
4X9C	D	60	Uncharacterized protein MJ1435	View
4X9C	E	56	Uncharacterized protein MJ1435	View
4X9C	F	56	Uncharacterized protein MJ1435	View
4XK8	E	63	Putative uncharacterized protein	View
4XQ3	B	77	Like-Sm ribonucleoprotein core	View
4XQ3	E	77	Like-Sm ribonucleoprotein core	View
4Y28	E	66	Putative uncharacterized protein	View
4ZCE	A	48	Dust mite allergen	View
4ZCE	B	48	Dust mite allergen	View
4ZGL	E	83	Uncharacterized HIT-like protein HP_0404	View
4ZQY	A	65	Ringhalexin	View
4ZQY	B	65	Ringhalexin	View
4ZQY	C	65	Ringhalexin	View
5C6P	B	91	Protein B	View
5D7U	A	53	Pol polyprotein	View
5D7U	B	52	Pol polyprotein	View
5DMA	A	53	ATP-dependent DNA helicase PcrA	View
5DO6	A	57	Mambalgin-1	View
5DO6	B	57	Mambalgin-1	View
5E8D	A	43	Proepiregulin	View
5EIN	C	54	OrfF	View
5HLZ	D	82	Inhibin beta A chain	View
5HLZ	F	86	Inhibin beta A chain	View
5HLZ	H	84	Inhibin beta A chain	View
5K2M	F	53	Probable lysine biosynthesis protein	View
5L23	A	58	Adapter molecule crk	View
5L8R	E	66	Putative uncharacterized protein	View
5SXP	A	61	Rho guanine nucleotide exchange factor 7	View
5SXP	B	61	Rho guanine nucleotide exchange factor 7	View
5SXP	C	60	Rho guanine nucleotide exchange factor 7	View
5SXP	D	60	Rho guanine nucleotide exchange factor 7	View
5UDZ	B	139	Protein lin-28 homolog A	View
1C6V	X	55	Pol polyprotein	View
1C9O	A	66	Cold shock protein CspB	View
1CDT	A	60	Cytotoxin 4	View
1CKA	A	57	Adapter molecule crk	View
1CSK	A	58	Tyrosine-protein kinase CSK	View
1D3B	B	81	Small nuclear ribonucleoprotein-associated proteins B and B'	View
1FAS	A	61	Fasciculin-1	View
1FF4	A	65	Muscarinic toxin 2	View
1GCQ	C	69	Proto-oncogene vav	View
1H34	A	57	Bowman-Birk type proteinase inhibitor	View
1IGQ	A	54	Transcriptional repressor protein KorB	View
1JB0	E	69	Photosystem I reaction center subunit IV	View
1JO8	A	58	Actin-binding protein	View
1KXI	A	62	Cytotoxin A5	View
1MJC	A	69	Cold shock protein CspA	View
1OOT	A	58	LAS seventeen-binding protein 3	View
1PI2	A	61	Bowman-Birk type proteinase inhibitor D-II	View
1PWT	A	61	Spectrin alpha chain, non-erythrocytic 1	View
1QM7	A	61		View
1R8O	A	96	Kunitz trypsin inhibitor	View
1RK8	C	33	Partner of Y14 and mago	View
1RUW	A	69	Myosin-3	View
1SEM	A	58	Sex muscle abnormal protein 5	View
1SMX	A	87	Ribonuclease E	View
1TG0	A	66	Myosin tail region-interacting protein MTI1	View
1TGX	A	60	Cytotoxin 1	View
1UG4	A	60	Cytotoxin 6	View
1UJ0	A	58	Signal transducing adapter molecule 2	View
1UOY	A	64	Bubble protein	View
1UTI	A	57	GRB2-related adaptor protein 2	View
1V6P	A	62	Cobrotoxin	View
1VB0	A	61	Cobrotoxin-b	View
1W70	A	60	Neutrophil cytosol factor 4	View
1WYX	A	68	Breast cancer anti-estrogen resistance protein 1	View
1Y0M	A	61	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	View
1YN8	A	59	NAP1-binding protein 2	View
1ZLM	A	58	Osteoclast-stimulating factor 1	View
1ZUU	A	56	Protein BZZ1	View
1ZUY	A	58	Myosin-5	View
2A08	A	59	Protein YSC84	View
2AYD	A	76	WRKY transcription factor 1	View
2B8M	A	105	Uncharacterized protein MJ0764	View
2BZ8	A	57	SH3 domain-containing kinase-binding protein 1	View
2DRM	A	58	Myosin heavy chain IB	View
2FPE	A	61	C-Jun-amino-terminal kinase-interacting protein 1	View
2G81	I	56	Serine protease ISO-inhibitor FIV	View
2GEC	A	138	Nucleoprotein	View
2GNC	A	55	SLIT-ROBO Rho GTPase-activating protein 1	View
2H8U	A	65	Bucain	View
2HDA	A	59	Tyrosine-protein kinase Yes	View
2HLR	A	67	Bone morphogenetic protein type II receptor	View
2IIM	A	62	Tyrosine-protein kinase Lck	View
2J05	A	61	Ras GTPase-activating protein 1	View
2O9S	A	67	Sorbin and SH3 domain-containing protein 1	View
2RH2	A	58	Dihydrofolate reductase type 2	View
2V1Q	A	60	Actin cytoskeleton-regulatory complex protein SLA1	View
2V1R	A	67	Peroxisomal membrane protein PAS20	View
2VKN	A	66	High osmolarity signaling protein SHO1	View
2VWF	A	56	Growth factor receptor-bound protein 2	View
3EBX	A	62	Erabutoxin b	View
3MYW	I	55	Bowman-Birk type trypsin inhibitor	View
4IIM	A	57	Intersectin-1	View
5MG9	A	65		View
5O99	A	60	SH3 and multiple ankyrin repeat domains protein 3	View
5OAV	A	57	Proto-oncogene tyrosine-protein kinase Src	View

Topology view of query protein [ProLego results]

2PKA : A

Topology Information