Protein Detail

Protein Information

PDBId & Chain	2RFA : A
Molecule	Transient receptor potential cation channel subfamily V member 6
Residues	222
Sequence
SSE Sequence^*(12)	`HHHHHHHHHHHH`

^* Secondary structure Elements (SSE) from N to C terminal of the PDB chain. [SSE: H ("Alpha Helix"); E ("Strands")]

Protein Topology

Topology Information

Protein topology is represented by contact and orientation of secondary structure elements (SSEs). The figure on the left represents the contact map with information on type of orientation two SSEs share (color coded). The matrix can be represented in following string representation.

Contact String
cs [Click here to expand] `Ha.0.Ha.0.Ha.0.Ha.0.Ha.0.Ha-Hp.Hp.Hp.Hp.Hp.Hp.Hp.Hp.Hp.Hp-Ha.0.0.0.Ha.0.Ha.0.0-0.0.0.0.0.0.0.0-0.0.0.0.0.0.0-0.0.0.0.0.0-0.0.0.0.0-0.0.0.0-0.0.0-0.0-0`

Prefence of topology : False

[ Hover over the plot rectangles to know more about SSE-contact ]

Linear Topology Graph : 2RFA_A

Protein Id: 2RFA_A

Figure Detail - Blocks: Helix (rectangles), Strands (triangles); Colormap: Red (N-terminal),--(Green)-- Blue (C-Terminal). Spatial Connectivity by arc Lines [Hover over the image to know the SSE detail]

Topology Graph : 2RFA_A

Protein Id: 2RFA_A

Expand

Figure Detail - Blocks: Helix (circle), Strands (arrow); Colormap: Red (N-terminal), Blue (C-Terminal). Spatial Connectivity by dotted Lines [Hover over the image to know the SSE detail]

Modules in queried Topology

#SSE	SSE string	Contact String	Preferrence	ProteinDB	DomainsDB
3	HHH	Ha.0-Hp	False	4YVQ:A, 5B1A:H, 5B1A:U, 5WGB:B,	d3ag3h_, 1se7A00, 1v54H00,
3	HHH	0.Ha-Hp	False	3RET:A, 3RET:B, 3RMI:A, 4RNG:D, 5VHT:A, 5VHT:B, 1ECM:A, 2WT7:B,	d1ecma_, d1ybza1, d3reta_, 1ecmA00,
4	HHHH	Ha.0.Ha-Hp.Hp-Ha	True	4M70:A, 4M70:H, 4M70:I, 4M70:L, 4M70:Q,
4	HHHH	Ha.0.Ha-Hp.Hp-0	False	3HPH:F,
6	HHHHHH	Ha.0.Ha.0.Ha-Hp.Hp.Hp.Hp-0.0.Ha-0.0-0	False
6	HHHHHH	Ha.0.Ha.0.Ha-Hp.Hp.Hp.Hp-Ha.0.Ha-0.0-0	False	2XEN:A, 2ZGD:A,
7	HHHHHHH	Ha.0.Ha.0.Ha.0-Hp.Hp.Hp.Hp.Hp-Ha.0.Ha.0-0.0.0-0.0-0	False
8	HHHHHHHH	Ha.0.Ha.0.Ha.0.Ha-Hp.Hp.Hp.Hp.Hp.Hp-Ha.0.0.0.Ha-0.0.0.0-0.0.0-0.0-0	False	5JA4:D,
8	HHHHHHHH	Ha.0.Ha.0.Ha.0.Ha-Hp.Hp.Hp.Hp.Hp.Hp-0.0.Ha.0.Ha-0.0.0.0-0.0.0-0.0-0	False
8	HHHHHHHH	Ha.0.Ha.0.Ha.0.Ha-Hp.Hp.Hp.Hp.Hp.Hp-Ha.0.Ha.0.0-0.0.0.0-0.0.0-0.0-0	False	3HG0:D, 3ZUV:B,

Protein In ProLegoDB with identical/similar Topology

Proteins with Identical Topology

[Same secondary structure composition, contact-pair and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Protein with similar Topology [same scaffold]

[Same secondary structure composition and contact-pair but of different orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology

Proteins with topologies of same secondary structure (H/E) component

[Topologies with same secondary structure composition with different contact-pairs and orientation]

PDB Id	Chain	Residues	Molecule	Detail Topology
2YG9	A	207	DNA-3-methyladenine glycosidase II, putative	View
2YG9	B	206	DNA-3-methyladenine glycosidase II, putative	View
2Z0V	A	216	Endophilin-A3	View
3ABH	A	278	Protein kinase C and casein kinase substrate in neurons protein 2	View
3B57	A	176	Lin1889 protein	View
3BJB	C	171	Probable transcriptional regulator, TetR family protein	View
3BJB	F	176	Probable transcriptional regulator, TetR family protein	View
3BYI	A	211	Rho GTPase-activating protein 15	View
3BYI	B	211	Rho GTPase-activating protein 15	View
3BYI	C	210	Rho GTPase-activating protein 15	View
3BYI	D	209	Rho GTPase-activating protein 15	View
3C02	A	242	Aquaglyceroporin	View
3C1L	A	174	Alkyl hydroperoxide reductase AhpD	View
3C1L	B	177	Alkyl hydroperoxide reductase AhpD	View
3C1L	C	175	Alkyl hydroperoxide reductase AhpD	View
3C1L	D	172	Alkyl hydroperoxide reductase AhpD	View
3C1L	E	173	Alkyl hydroperoxide reductase AhpD	View
3C1L	F	173	Alkyl hydroperoxide reductase AhpD	View
3C1L	G	176	Alkyl hydroperoxide reductase AhpD	View
3C1L	H	172	Alkyl hydroperoxide reductase AhpD	View
3C1L	I	173	Alkyl hydroperoxide reductase AhpD	View
3C1L	J	175	Alkyl hydroperoxide reductase AhpD	View
3C1L	K	173	Alkyl hydroperoxide reductase AhpD	View
3C1L	L	173	Alkyl hydroperoxide reductase AhpD	View
3C2B	A	198	Transcriptional regulator, TetR family	View
3C2B	B	192	Transcriptional regulator, TetR family	View
3CJD	A	177	Transcriptional regulator, TetR family	View
3CJD	B	177	Transcriptional regulator, TetR family	View
3CRJ	D	184	Transcription regulator	View
3D31	C	248	Sulfate/molybdate ABC transporter, permease protein	View
3D31	D	248	Sulfate/molybdate ABC transporter, permease protein	View
3DCF	A	183	Transcriptional regulator, TetR family	View
3DCF	B	181	Transcriptional regulator, TetR family	View
3DEW	A	186	Transcriptional regulator, TetR family	View
3DJB	A	180	Hydrolase, HD family	View
3DJB	B	180	Hydrolase, HD family	View
3DPJ	B	184	Transcription regulator, TetR family	View
3DPJ	F	182	Transcription regulator, TetR family	View
3DYJ	A	311	Talin-1	View
3DYJ	B	311	Talin-1	View
3E0S	B	294	Uncharacterized protein	View
3EDT	B	258	Kinesin light chain 2	View
3EDT	D	255	Kinesin light chain 2	View
3EDT	F	258	Kinesin light chain 2	View
3EDT	H	254	Kinesin light chain 2	View
3EE4	A	289	R2-like ligand binding oxidase	View
3EYB	A	199	Nuclear hormone receptor RXR	View
3EYB	B	199	Nuclear hormone receptor RXR	View
3EYB	C	199	Nuclear hormone receptor RXR	View
3EYB	D	199	Nuclear hormone receptor RXR	View
3FHG	A	207	Probable N-glycosylase/DNA lyase	View
3GZI	A	196	Transcriptional regulator, TetR family	View
3HE0	A	178	Transcriptional regulator, TetR family	View
3HE0	B	174	Transcriptional regulator, TetR family	View
3HE0	C	182	Transcriptional regulator, TetR family	View
3HRA	A	199	Ankyrin repeat family protein	View
3IBX	A	221	Aminopyrimidine aminohydrolase	View
3ISM	C	286	SD16985p	View
3KCU	C	239	Probable formate transporter 1	View
3KCU	D	248	Probable formate transporter 1	View
3KKD	B	199	Probable transcriptional regulator	View
3KNW	A	174	Putative transcriptional regulator (TetR/AcrR family)	View
3KRA	B	259	Gpp synthase small subunit	View
3N0U	A	209	Probable N-glycosylase/DNA lyase	View
3N0U	B	209	Probable N-glycosylase/DNA lyase	View
3N0U	C	208	Probable N-glycosylase/DNA lyase	View
3NI7	B	164	Bacterial regulatory proteins, TetR family	View
3OQL	C	232	Uncharacterized protein	View
3PAS	A	187	Transcriptional regulator	View
3PAS	B	189	Transcriptional regulator	View
3PAS	C	188	Transcriptional regulator	View
3PAS	D	188	Transcriptional regulator	View
3QKC	A	256	Geranyl diphosphate synthase small subunit	View
3QKC	B	256	Geranyl diphosphate synthase small subunit	View
3RRW	A	252	Thylakoid lumenal 29 kDa protein, chloroplastic	View
3RRW	B	249	Thylakoid lumenal 29 kDa protein, chloroplastic	View
3RV1	A	217	Putative uncharacterized protein	View
3SWH	A	295	Protein unc-13 homolog A	View
3TDS	A	257	Putative formate/nitrite transporter	View
3TDS	B	257	Putative formate/nitrite transporter	View
3TDS	C	266	Putative formate/nitrite transporter	View
3TDS	D	257	Putative formate/nitrite transporter	View
3TDS	E	256	Putative formate/nitrite transporter	View
3UIT	A	256	Protein lin-7 homolog B	View
3UIT	B	253	Protein lin-7 homolog B	View
3UIT	C	255	Protein lin-7 homolog B	View
3UIT	D	257	Protein lin-7 homolog B	View
3WI3	A	215	DNA replication regulator SLD3	View
3WI3	C	205	DNA replication regulator SLD3	View
4BGO	A	251	Uncharacterized protein	View
4BVN	A	289	Beta-1 adrenergic receptor	View
4C9B	B	277	Pre-mRNA-splicing factor CWC22 homolog	View
4C9G	A	265	ADP,ATP carrier protein 2	View
4CAD	C	251	CAAX prenyl protease 2	View
4CAD	F	250	CAAX prenyl protease 2	View
4CAD	I	254	CAAX prenyl protease 2	View
4CAD	L	253	CAAX prenyl protease 2	View
4CEK	A	240	Regulator of nonsense transcripts 2	View
4F62	B	255	Geranyltranstransferase	View
4FC4	A	249	Nitrite transporter NirC	View
4FC4	B	250	Nitrite transporter NirC	View
4FC4	C	250	Nitrite transporter NirC	View
4FC4	D	249	Nitrite transporter NirC	View
4FC4	E	250	Nitrite transporter NirC	View
4FC4	F	250	Nitrite transporter NirC	View
4FC4	G	248	Nitrite transporter NirC	View
4FC4	H	250	Nitrite transporter NirC	View
4FC4	I	250	Nitrite transporter NirC	View
4FC4	J	250	Nitrite transporter NirC	View
4FP4	A	243	Polyprenyl synthetase	View
4G9Q	A	236	4-carboxymuconolactone decarboxylase	View
4GYV	A	212	FERM, RhoGEF and pleckstrin domain-containing protein 2	View
4GYV	C	212	FERM, RhoGEF and pleckstrin domain-containing protein 2	View
4GYV	H	212	FERM, RhoGEF and pleckstrin domain-containing protein 2	View
4HI0	A	227	Urease accessory protein UreF	View
4HI0	C	227	Urease accessory protein UreF	View
4HTP	A	221	DNA ligase 4	View
4HTP	B	222	DNA ligase 4	View
4I17	A	221	Putative exported protein	View
4J4Y	A	250	NP protein	View
4J4Y	C	251	NP protein	View
4LOG	B	232	Photoreceptor-specific nuclear receptor	View
4M1H	A	331	Ribonucleoside-diphosphate reductase subunit beta	View
4MK6	A	183	Lmo0480 protein	View
4N2X	A	298	DL-2-haloacid dehalogenase	View
4N2X	B	298	DL-2-haloacid dehalogenase	View
4N2X	D	298	DL-2-haloacid dehalogenase	View
4N2X	E	298	DL-2-haloacid dehalogenase	View
4N2X	F	298	DL-2-haloacid dehalogenase	View
4N2X	G	298	DL-2-haloacid dehalogenase	View
4NST	B	246	Cyclin-K	View
4NST	D	241	Cyclin-K	View
4QMH	A	236	Mini spindles, isoform C	View
4QMI	B	225	Cytoskeleton-associated protein 5	View
4RAJ	A	216	Heme oxygenase	View
4RD8	B	212	Uncharacterized protein	View
4RHP	B	196	Ubiquinone biosynthesis protein COQ9, mitochondrial	View
4UOB	A	242	Endonuclease III, putative	View
4X82	A	227	Zinc transporter ZIP4	View
4X8Q	A	207	Uncharacterized protein	View
5AAR	A	185	Potassium channel AKT1	View
5B00	A	261	MoeN5	View
5CEC	B	193	Uncharacterized protein	View
5CER	B	193	Uncharacterized protein	View
5CER	D	193	Uncharacterized protein	View
5CER	F	193	Uncharacterized protein	View
5CER	H	193	Uncharacterized protein	View
5CER	J	193	Uncharacterized protein	View
5CER	L	193	Uncharacterized protein	View
5COW	A	234	Putative uncharacterized protein	View
5CS0	A	215	Acetyl-CoA carboxylase	View
5CSM	A	250	Chorismate mutase	View
5DAJ	A	192	NalD	View
5DAJ	B	190	NalD	View
5DAJ	C	190	NalD	View
5DAJ	D	187	NalD	View
5DAJ	E	188	NalD	View
5DAJ	F	188	NalD	View
5DAJ	G	193	NalD	View
5DAJ	H	191	NalD	View
5EFQ	D	239	Cyclin-K	View
5EIK	A	234	Uncharacterized protein	View
5F0Q	A	187	DNA primase large subunit	View
5F0Q	B	185	DNA primase large subunit	View
5HVX	A	256	Ion transport protein	View
5KLB	B	267	Ion transport protein	View
5KLB	D	267	Ion transport protein	View
5KN8	A	222	Adenine DNA glycosylase	View
1AOA	A	247	Plastin-3	View
1EYS	M	318		View
1FYH	A	242	Interferon gamma	View
1H6G	A	248	Catenin alpha-1	View
1KEA	A	217	G/T mismatches repair enzyme	View
1KXU	A	276	Cyclin-H	View
1MUN	A	225	Adenine DNA glycosylase	View
1OGL	A	246	Deoxyuridine triphosphatase	View
1ORN	A	214		View
1OY3	D	220	NF-kappa-B inhibitor beta	View
1QAZ	A	351	Alginate lyase	View
1QQF	A	276	Complement C3	View
1RCW	A	209	PqqC-like protein	View
1RZH	M	301	Reaction center protein M chain	View
1T33	A	220	Putative transcriptional repressor (TetR/AcrR family)	View
1TX4	A	196	Rho GTPase-activating protein 1	View
1UI5	A	195	CprB	View
1W98	B	270	G1/S-specific cyclin-E1	View
1WE1	A	222	Heme oxygenase 1	View
1Z7L	A	255	Ubiquitin-like modifier-activating enzyme 1	View
2A2M	A	225	TenA family transcriptional activator-like protein	View
2D6Y	A	182	HTH-type transcriptional repressor SCO4008	View
2ETB	A	252	Transient receptor potential cation channel subfamily V member 2	View
2F2C	A	244	Cyclin homolog	View
2F37	A	244	Transient receptor potential cation channel subfamily V member 2	View
2GM8	A	217	Conserved protein (TenA homolog)	View
2HYT	A	188	TetR-family transcriptional regulator	View
2I10	A	173	Transcriptional regulator, TetR family protein	View
2IBN	A	231	Inositol oxygenase	View
2IPB	A	219	Acid phosphatase	View
2IVX	A	256	Cyclin-T2	View
2JJ7	A	177	Hemolysin II regulatory protein	View
2OEX	A	338	Programmed cell death 6-interacting protein	View
2OGI	A	190	Uncharacterized protein	View
2PFX	A	178	Alkyl hydroperoxide reductase AhpD	View
2PRR	A	184	Alkyl hydroperoxide reductase AhpD	View
2Q12	A	231	DCC-interacting protein 13-alpha	View
2Q7F	A	194	TPR repeat-containing protein YrrB	View
2QF9	A	148	Putative secreted protein	View
2QTQ	A	199	Transcriptional regulator, TetR family	View
2R5S	A	170	Uncharacterized protein	View
2RAS	A	190	Transcriptional regulator, TetR family	View
2RFM	A	183	Putative ankyrin repeat protein TV1425	View
2WY8	A	292	Complement C3	View

Topology view of query protein [ProLego results]

2RFA : A

Topology Information